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Image Search Results
Journal: Membranes
Article Title: Cell Surface Binding and Lipid Interactions behind Chemotherapy-Drug-Induced Ion Pore Formation in Membranes
doi: 10.3390/membranes11070501
Figure Lengend Snippet: Top-left panel ( a ), high resolution TM-AFM image of a control (colchicine untreated) cell surface. Top-right panel ( b ), histograms presented here are based on counted clusters on the section of cell surface shown in the left panel ( a ). Each histogram represents the number of counted clusters (called frequency, let us assume it as f i , plotted along y-axis. i = 1, 2, 3, …, etc.) versus a height profile (known as particle height, b (top-right panel), let us assume it as h i , plotted in nm scale along x-axis) shown in b. As mentioned in , the height profiles are recorded at the centers of the corresponding clusters (see the left panel), a. Middle and bottom panels present data for cells treated with 1 and 100 µM colchicine, respectively. The higher presence of clusters (in green color) on blue background is visible. We repeated the experiments three times but inspected no substantial changes in the distribution patterns presented in the right panels. Origin 9.1 was used to plot histograms after detecting the numbers using program WSxM. The origin of the detected few events (visible in log plots, see in insets of b) for untreated/control cell surface is nothing but noise.
Article Snippet: Two different AFMs were used: Tapping Mode of
Techniques: